Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.42 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL883728 | 0.71 | — | — | |
| SCHEMBL8710289 | 0.71 | KDR (0.34) | UHRF1SMARCA2SMARCA4KDRHDAC3 | |
| SCHEMBL27629951 | 0.70 | — | — | |
| SCHEMBL2476869 | 0.70 | — | — | |
| SCHEMBL10138666 | 0.70 | — | — | |
| SCHEMBL2885926 | 0.70 | — | — | |
| SCHEMBL7659797 | 0.69 | NPSR1 (0.53) | UHRF1SMARCA2SMARCA4KDRHDAC3 | |
| SCHEMBL31494286 | 0.69 | NPSR1 (0.53) | UHRF1SMARCA2SMARCA4KDRHDAC3 | |
| Bromide SCHEMBL16633264 | 0.68 | UHRF1 (0.48) | UHRF1SMARCA2SMARCA4KDRHDAC3 | |
| Hydrochloric Acid SCHEMBL27472049 | 0.68 | UHRF1 (0.48) | UHRF1SMARCA2SMARCA4KDRHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1184969-C | Use of unsubstd and substd. N-(pyrrol-1-yl) pyridinamines as anticonvulsant agents | AVENTIS PHARMA INC (US) | 2005-01-19 | — | — | CN | claimed |
| CN-1191486-A | Use of unsubstituted and substituted N- (pyrrol-1-yl) pyridinamines as anticonvulsants | HOECHST MARION ROUSSEL INC (US) | 1998-08-26 | — | — | CN | claimed |
| EP-0840609-A1 | USE OF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1998-05-13 | — | — | EP | claimed |
| WO-1997004777-A1 | USE OFF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1997-02-13 | — | — | WO | claimed |
| CN-1184969-C | Use of unsubstd and substd. N-(pyrrol-1-yl) pyridinamines as anticonvulsant agents | AVENTIS PHARMA INC (US) | 2005-01-19 | — | — | CN | disclosed |
| CN-1191486-A | Use of unsubstituted and substituted N- (pyrrol-1-yl) pyridinamines as anticonvulsants | HOECHST MARION ROUSSEL INC (US) | 1998-08-26 | — | — | CN | disclosed |