Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8050250 | 0.91 | ALDH1A1 (0.34) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL8043988 | 0.86 | MEN1 (0.44) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8043229 | 0.79 | MEN1 (0.36) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL8051739 | 0.79 | ALDH1A1 (0.37) | ALDH1A1MAPTSMN1; SMN2TSHR | |
| SCHEMBL8046531 | 0.77 | PTGS1 (0.32) | — | |
| SCHEMBL8032336 | 0.75 | PTGS1 (0.32) | — | |
| SCHEMBL8042604 | 0.74 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL8044871 | 0.74 | ATM (0.42) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8048226 | 0.74 | MEN1 (0.45) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8042342 | 0.74 | PTGS1 (0.33) | MEN1KMT2AALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998027092-A1 | THIAZOLE COMPOUNDS AND METHODS OF MODULATING SIGNAL TRANSDUCTION | SUGEN, INC. (US) | 1998-06-25 | — | — | WO | disclosed |