Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 15/20 | 0.44 |
| ▸ | PDE4A | P27815 | 13/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8707864 | 0.87 | PDE4B (0.53) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8710983 | 0.86 | PDE4B (0.46) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL8712873 | 0.86 | PDE4B (0.52) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8707100 | 0.85 | PDE4B (0.42) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL8707496 | 0.81 | PDE4B (0.46) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8711449 | 0.78 | HTR2C (0.49) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7688170 | 0.78 | PDE4B (0.57) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8708786 | 0.77 | PDE4D (0.43) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL8713399 | 0.77 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8707072 | 0.77 | PDE4B (0.46) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042666-A1 | NOVEL 3,4-DIALKOXYPHENYL DERIVATIVES AND THE USE THEREOF | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 1998-10-01 | — | — | WO | disclosed |