Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 14/20 | 0.43 |
| ▸ | PDE4A | P27815 | 12/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 11/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | VEGFA | P15692 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8707002 | 0.88 | L3MBTL1 (0.41) | PDE4DPDE4APDE4BPDE4CL3MBTL1 | |
| SCHEMBL8714452 | 0.88 | L3MBTL1 (0.50) | L3MBTL1RXFP1ALDH1A1LMNACYP2C9 | |
| SCHEMBL8710571 | 0.88 | PDE4B (0.42) | PDE4DPDE4APDE4BPDE4CL3MBTL1 | |
| SCHEMBL8707864 | 0.85 | PDE4B (0.53) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL8712873 | 0.84 | PDE4B (0.52) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL8707496 | 0.83 | PDE4B (0.46) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL8707973 | 0.81 | L3MBTL1 (0.41) | PDE4DPDE4APDE4BPDE4CL3MBTL1 | |
| SCHEMBL8710983 | 0.80 | PDE4B (0.46) | PDE4DPDE4APDE4BPDE4CVEGFA | |
| SCHEMBL7688170 | 0.79 | PDE4B (0.57) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL8713399 | 0.78 | PDE4B (0.56) | PDE4DPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042666-A1 | NOVEL 3,4-DIALKOXYPHENYL DERIVATIVES AND THE USE THEREOF | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 1998-10-01 | — | — | WO | disclosed |