Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18596695 | 0.92 | ALDH1A1 (0.54) | ALDH1A1GAATSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL3555994 | 0.87 | EPHX2 (0.47) | ALDH1A1GAATSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL885125 | 0.83 | ALDH1A1 (0.62) | ALDH1A1GAATSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL12543513 | 0.82 | ALDH1A1 (0.61) | ALDH1A1GAATSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL2303769 | 0.82 | ALDH1A1 (0.61) | ALDH1A1GAATSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL19808633 | 0.82 | ALDH1A1 (0.61) | ALDH1A1GAATSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL1543240 | 0.80 | ALDH1A1 (0.42) | ALDH1A1GAATSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL13853552 | 0.80 | ALDH1A1 (0.59) | ALDH1A1GAATSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL12448213 | 0.80 | ALDH1A1 (0.59) | ALDH1A1GAATSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL6358125 | 0.80 | KMT2A (0.59) | ALDH1A1GAATSHRL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593079-B1 | MENTHYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | SYMRISE AG (DE) | 2016-11-16 | — | — | EP | disclosed |
| US-9060949-B2 | Menthyl carbamate compounds as skin and/or hair lightening actives | SYMRISE AG (DE) | 2015-06-23 | — | — | US | disclosed |
| US-20130129646-A1 | MENTHYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | SYMRISE AG (DE) | 2013-05-23 | — | — | US | disclosed |
| EP-0885239-A1 | NOVEL STEROID CARBAMATES AS POTENTIATING AGENTS | Batra, Satish (SE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997027211-A1 | NOVEL STEROID CARBAMATES AS POTENTIATING AGENTS | BATRA SATISH (SE) | 1997-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130129646-A1 | MENTHYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | TYR, CRAT, SUCLG1 | ALDH1A1 160/4885GAA 4041/4885TSHR 2082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.