Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | ACE | P12821 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | APAF1 | O14727 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MPO | P05164 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.61 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.61 |
| ▸ | ITGAL | P20701 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8710928 | 1.00 | SMN1; SMN2 (0.68) | SMN1; SMN2ALOX15ACEKDM4EMAPT | |
| Konbamidin SCHEMBL6277606 | 0.90 | ALOX15 (0.64) | SMN1; SMN2ALOX15ACEKDM4EMAPT | |
| SCHEMBL29773000 | 0.89 | ALOX15 (0.65) | SMN1; SMN2ALOX15ACEKDM4EMAPT | |
| SCHEMBL150050 | 0.89 | ALOX15 (0.65) | SMN1; SMN2ALOX15ACEKDM4EMAPT | |
| SCHEMBL9115508 | 0.89 | ALOX15 (0.65) | SMN1; SMN2ALOX15ACEKDM4EMAPT | |
| SCHEMBL22654181 | 0.89 | ALOX15 (0.65) | SMN1; SMN2ALOX15ACEKDM4EMAPT | |
| SCHEMBL9115505 | 0.89 | ALOX15 (0.65) | SMN1; SMN2ALOX15ACEKDM4EMAPT | |
| SCHEMBL6010110 | 0.89 | SMN1; SMN2 (0.60) | SMN1; SMN2ALOX15ACEKDM4EMAPT | |
| SCHEMBL6010119 | 0.89 | SMN1; SMN2 (0.60) | SMN1; SMN2ALOX15ACEKDM4EMAPT | |
| SCHEMBL29171716 | 0.88 | ALOX15 (0.68) | SMN1; SMN2ALOX15ACEKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552489-B1 | Peptide, production and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-03-04 | — | — | EP | disclosed |
| EP-0626174-A2 | Methods and compositions for the prophylactic and/or therapeutic treatment of organ hypofunction | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-11-30 | — | — | EP | disclosed |
| EP-0552489-A2 | Peptide, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-07-28 | — | — | EP | disclosed |