Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | ITGB2 | P05107 | 5/20 | 0.65 |
| ▸ | ICAM1 | P05362 | 5/20 | 0.65 |
| ▸ | ITGAL | P20701 | 5/20 | 0.65 |
| ▸ | ACE | P12821 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | APAF1 | O14727 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MPO | P05164 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9115505 | 1.00 | ALOX15 (0.65) | ALOX15ITGB2ICAM1ITGALACE | |
| SCHEMBL8710928 | 0.89 | SMN1; SMN2 (0.68) | ALOX15ITGB2ICAM1ITGALACE | |
| SCHEMBL150050 | 0.89 | ALOX15 (0.65) | ALOX15ITGB2ICAM1ITGALACE | |
| SCHEMBL29773000 | 0.89 | ALOX15 (0.65) | ALOX15ITGB2ICAM1ITGALACE | |
| SCHEMBL22654181 | 0.89 | ALOX15 (0.65) | ALOX15ITGB2ICAM1ITGALACE | |
| SCHEMBL8710933 | 0.89 | SMN1; SMN2 (0.68) | ALOX15ITGB2ICAM1ITGALACE | |
| SCHEMBL3451205 | 0.88 | ALOX15 (0.67) | ALOX15ITGB2ICAM1ITGALACE | |
| SCHEMBL22127126 | 0.88 | ALOX15 (0.64) | ALOX15ITGB2ICAM1ITGALACE | |
| SCHEMBL5123003 | 0.88 | ALOX15 (0.67) | ALOX15ITGB2ICAM1ITGALACE | |
| SCHEMBL3451206 | 0.88 | ALOX15 (0.67) | ALOX15ITGB2ICAM1ITGALACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11878002-B2 | Methods and materials for using Ruminococcus gnavus or Clostridium sporogenes to treat gastrointestinal disorders | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2024-01-23 | — | — | US | disclosed |
| US-10993930-B2 | Methods and materials for using Ruminococcus gnavus or Clostridium sporogenes to treat gastrointestinal disorders | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2021-05-04 | — | — | US | disclosed |
| US-10300043-B2 | Method for treating a gastrointestinal disorder in a mammal using bacteroides thetaiotaomicron and compositions thereof | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2019-05-28 | — | — | US | disclosed |
| US-20170042860-A1 | METHODS AND MATERIALS FOR USING RUMINOCOCCUS GNAVUS OR CLOSTRIDIUM SPOROGENES TO TREAT GASTROINTESTINAL DISORDERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-02-16 | — | — | US | disclosed |
| WO-1995011878-A1 | INHIBITORS OF KYNURENINASE | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1995-05-04 | — | — | WO | disclosed |