Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD1 | P21728 | 2/20 | 0.37 |
| ▸ | DRD5 | P21918 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6875130 | 0.82 | PDE4B (0.48) | ESR1ESR2PDK2NOTUMPDE4B | |
| SCHEMBL27315440 | 0.80 | ALDH1A1 (0.47) | NOTUMALDH1A1KMT2ANPSR1 | |
| SCHEMBL13625257 | 0.76 | TP53 (0.44) | ESR1ESR2PDK2ALDH1A1MAPT | |
| SCHEMBL8710132 | 0.74 | ALDH1A1 (0.39) | ESR1ESR2HSD17B10NOTUMKDM4E | |
| SCHEMBL6937210 | 0.74 | MAPT (0.54) | ESR1ESR2KDM4EALDH1A1MAPT | |
| SCHEMBL22073771 | 0.73 | MAPT (0.56) | PDK2NOTUMKDM4ETSHRALDH1A1 | |
| SCHEMBL30559652 | 0.73 | PDK2 (0.61) | ESR1ESR2PDK2KMT2AMAPT | |
| SCHEMBL9937344 | 0.73 | PDK2 (0.61) | ESR1ESR2PDK2KMT2AMAPT | |
| SCHEMBL30680392 | 0.72 | ALDH1A1 (0.53) | KDM4EALDH1A1MAPTRAB9ADRD2 | |
| SCHEMBL2763754 | 0.72 | ALDH1A1 (0.53) | KDM4EALDH1A1MAPTRAB9ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0852486-A2 | ANTIPLAQUE ORAL COMPOSITION | Colgate-Palmolive Company (US) | 1998-07-15 | — | — | EP | disclosed |
| US-5723500-A | WATER INSOLUBLE, NONCATIONIC, ANTIBACTERIAL, STERICALLY HINDERED PHENOL; MOUTHWASHES, DENTIFRICES | COLGATE-PALMOLIVE COMPANY (US) | 1998-03-03 | — | — | US | disclosed |
| WO-1997010800-A2 | ANTIPLAQUE ORAL COMPOSITION | COLGATE-PALMOLIVE COMPANY (US) | 1997-03-27 | — | — | WO | disclosed |