Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 4/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.41 |
| ▸ | RXRA | P19793 | 7/20 | 0.40 |
| ▸ | RARB | P10826 | 6/20 | 0.40 |
| ▸ | RARG | P13631 | 5/20 | 0.40 |
| ▸ | RXRB | P28702 | 5/20 | 0.40 |
| ▸ | RXRG | P48443 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 3/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23018664 | 0.85 | TP53 (0.35) | TP53CYP1A2PDK2ESR1ESR2 | |
| SCHEMBL1360287 | 0.84 | RXRA (0.49) | TP53CYP1A2RXRARARBRARG | |
| SCHEMBL30701838 | 0.84 | RXRA (0.49) | TP53CYP1A2RXRARARBRARG | |
| SCHEMBL8662092 | 0.81 | PBRM1 (0.53) | ESR1ESR2MAPTPBRM1CYP3A4 | |
| SCHEMBL31650524 | 0.81 | PBRM1 (0.53) | ESR1ESR2MAPTPBRM1CYP3A4 | |
| SCHEMBL12014319 | 0.79 | DRD2 (0.47) | TP53CYP1A2ESR1ESR2CYP3A4 | |
| SCHEMBL6937210 | 0.76 | MAPT (0.54) | ESR1ESR2MAPTPBRM1CYP3A4 | |
| SCHEMBL8711307 | 0.76 | ESR1 (0.47) | PDK2ESR1ESR2MAPTALDH1A1 | |
| SCHEMBL1495880 | 0.75 | ESR2 (0.58) | ESR1ESR2CYP3A4ALDH1A1LMNA | |
| SCHEMBL29890280 | 0.75 | ESR2 (0.58) | ESR1ESR2CYP3A4ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1724110-B1 | Multilayered articles and method of manufacture thereof | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2019-08-21 | — | — | EP | disclosed |
| US-10329422-B2 | Flame retardant laser direct structuring materials | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2019-06-25 | — | — | US | disclosed |
| US-20170342263-A1 | FLAME RETARDANT LASER DIRECT STRUCTURING MATERIALS | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2017-11-30 | — | — | US | disclosed |
| US-20170342263-A1 | FLAME RETARDANT LASER DIRECT STRUCTURING MATERIALS | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2017-11-30 | — | — | US | disclosed |
| EP-2678383-B1 | THERMALLY CONDUCTIVE AND ELECTRICALLY INSULATIVE POLYMER COMPOSITIONS CONTAINING A LOW THERMALLY CONDUCTIVE FILLER AND USES THEREOF | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2017-07-19 | — | — | EP | disclosed |
| US-20160362537-A1 | ENHANCED POLYCARBONATE EXTRUSION GRADES | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2016-12-15 | — | — | US | disclosed |
| US-9390744-B2 | Polycarbonate composition to produce optical quality products with high quality and good processability | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-07-12 | — | — | US | disclosed |
| US-9243125-B2 | Release polycarbonate compositions | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-01-26 | — | — | US | disclosed |
| US-9243125-B2 | Release polycarbonate compositions | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-01-26 | — | — | US | disclosed |
| US-9185800-B2 | Laser direct structuring materials with improved plating performance and acceptable mechanical properties | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2015-11-10 | — | — | US | disclosed |
| US-8741998-B2 | Thermally conductive and electrically insulative polymer compositions containing a thermally insulative filler and uses thereof | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2014-06-03 | — | — | US | disclosed |
| US-20140076616-A1 | LASER DIRECT STRUCTURING MATERIALS WITH IMPROVED PLATING PERFORMANCE AND ACCEPTABLE MECHANICAL PROPERTIES | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2014-03-20 | — | — | US | disclosed |
| US-20140076616-A1 | LASER DIRECT STRUCTURING MATERIALS WITH IMPROVED PLATING PERFORMANCE AND ACCEPTABLE MECHANICAL PROPERTIES | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2014-03-20 | — | — | US | disclosed |
| US-20130289178-A1 | FLAME RETARDANT LASER DIRECT STRUCTURING MATERIALS | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2013-10-31 | — | — | US | disclosed |
| US-8552101-B2 | Thermally conductive and electrically insulative polymer compositions containing a low thermally conductive filler and uses thereof | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2013-10-08 | — | — | US | disclosed |
| US-8492464-B2 | Flame retardant laser direct structuring materials | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2013-07-23 | — | — | US | disclosed |
| US-8492464-B2 | Flame retardant laser direct structuring materials | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2013-07-23 | — | — | US | disclosed |
| US-20090292048-A1 | FLAME RETARDANT LASER DIRECT STRUCTURING MATERIALS | SABIC INNOVATIVES PLASTICS IP B.V. (US) | 2009-11-26 | — | — | US | disclosed |
| US-20070225416-A1 | FLAME RETARDANT POLYCARBONATE COMPOSITIONS HAVING GOOD TRANSPARENCY AND LOW HAZE, METHOD OF MANUFACTURE, AND ARTICLES PREPARED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2007-09-27 | — | — | US | disclosed |
| US-7210926-B2 | Formable sheets for medical applications and methods of manufacture thereof | GENERAL ELECTRIC COMPANY (US) | 2007-05-01 | — | — | US | disclosed |