Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.69 |
| ▸ | DRD2 | P14416 | 1/20 | 0.62 |
| ▸ | DRD1 | P21728 | 1/20 | 0.62 |
| ▸ | DRD3 | P35462 | 1/20 | 0.62 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.62 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.62 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.60 |
| ▸ | GCGR | P47871 | 1/20 | 0.58 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8711348 | 0.88 | LTA4H (0.76) | LTA4HDRD2DRD1DRD3PSMB1 | |
| SCHEMBL13305534 | 0.83 | LTA4H (0.97) | LTA4HPSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL28380360 | 0.82 | LTA4H (1.00) | LTA4HDRD2DRD1DRD3PSMB1 | |
| SCHEMBL18595108 | 0.80 | HRH3 (0.71) | LTA4HPSMB1PSMB5KDM4EHRH3 | |
| SCHEMBL19172409 | 0.80 | HRH3 (0.71) | LTA4HPSMB1PSMB5KDM4EHRH3 | |
| SCHEMBL18265845 | 0.80 | HRH3 (0.71) | LTA4HPSMB1PSMB5KDM4EHRH3 | |
| SCHEMBL2741672 | 0.80 | HRH3 (0.71) | LTA4HPSMB1PSMB5KDM4EHRH3 | |
| Hydrochloric Acid SCHEMBL8693858 | 0.79 | KDM4E (0.63) | LTA4HPSMB1PSMB5PSMB2KDM4E | |
| Hydrochloric Acid SCHEMBL7054130 | 0.79 | KDM4E (0.73) | LTA4HPSMB1PSMB5PSMB2KDM4E | |
| Hydrochloric Acid SCHEMBL224629 | 0.79 | HRH3 (0.70) | LTA4HKDM4EHRH3ESR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821252-A | PROLONGED SPASMOLYTIC AND ANESTHETIC ACITIVITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-10-13 | — | — | US | disclosed |