Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.76 |
| ▸ | PSMB1 | P20618 | 4/20 | 0.73 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.73 |
| ▸ | PSMB2 | P49721 | 3/20 | 0.73 |
| ▸ | GCGR | P47871 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | DRD2 | P14416 | 1/20 | 0.65 |
| ▸ | DRD1 | P21728 | 1/20 | 0.65 |
| ▸ | DRD3 | P35462 | 1/20 | 0.65 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.64 |
| ▸ | ESR1 | P03372 | 3/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13305534 | 0.88 | LTA4H (0.97) | LTA4HPSMB1PSMB5PSMB2GCGR | |
| SCHEMBL8711352 | 0.88 | LTA4H (0.69) | LTA4HPSMB1PSMB5PSMB2GCGR | |
| Pitofenone SCHEMBL2111794 | 0.87 | KDM4E (0.69) | LTA4HPSMB1PSMB5PSMB2GCGR | |
| SCHEMBL28380360 | 0.87 | LTA4H (1.00) | LTA4HPSMB1PSMB5PSMB2GCGR | |
| Pitofenone SCHEMBL4389235 | 0.86 | KDM4E (0.67) | LTA4HPSMB1PSMB5PSMB2GCGR | |
| SCHEMBL7443174 | 0.85 | PSMB1 (0.70) | LTA4HPSMB1PSMB5PSMB2GCGR | |
| SCHEMBL7445638 | 0.84 | LTA4H (0.70) | LTA4HPSMB1PSMB5PSMB2GCGR | |
| SCHEMBL8714269 | 0.84 | PSMB1 (0.64) | LTA4HPSMB1PSMB5PSMB2GCGR | |
| Hydrochloric Acid SCHEMBL9191319 | 0.84 | PSMB1 (0.64) | LTA4HPSMB1PSMB5PSMB2GCGR | |
| SCHEMBL2741667 | 0.84 | PSMB1 (0.80) | LTA4HPSMB1PSMB5PSMB2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0364941-B1 | Branched-chain alkyl esters of 2-(4-(2-piperidino ethoxy)benzoyl)benzoic acid, processes for their preparation and their use as spasmolytic agents | HOECHST AG (DE) | 1995-02-15 | — | — | EP | claimed |
| JP-2169585-A | — | — | None | — | — | JP | disclosed |
| US-5821252-A | PROLONGED SPASMOLYTIC AND ANESTHETIC ACITIVITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-10-13 | — | — | US | disclosed |
| EP-0364941-B1 | Branched-chain alkyl esters of 2-(4-(2-piperidino ethoxy)benzoyl)benzoic acid, processes for their preparation and their use as spasmolytic agents | HOECHST AG (DE) | 1995-02-15 | — | — | EP | disclosed |
| EP-0364941-B1 | Branched-chain alkyl esters of 2-(4-(2-piperidino ethoxy)benzoyl)benzoic acid, processes for their preparation and their use as spasmolytic agents | HOECHST AG (DE) | 1995-02-15 | — | — | EP | disclosed |
| CN-1025615-C | Branched-chain alkyl esters of 2-[4-(2-piperidiono-ethoxy)-benzoyl]-benzoic acid, processes for their preparation and their use as spasmolytic agents | HOECHST AG (DE) | 1994-08-10 | — | — | CN | disclosed |
| CN-1025615-C | Branched-chain alkyl esters of 2-[4-(2-piperidiono-ethoxy)-benzoyl]-benzoic acid, processes for their preparation and their use as spasmolytic agents | HOECHST AG (DE) | 1994-08-10 | — | — | CN | disclosed |
| JP-H02169585-A | BRANCHED CHAIN ALKYL ESTER OF 2-(4-(2-PIPERIDINO-ETHOXY)-BENZOYL)BENZOATE AND ITS PRODUCTION | HOECHST AG | 1990-06-29 | — | — | JP | disclosed |
| EP-0364941-A1 | Branched-chain alkyl esters of 2-(4-(2-piperidino ethoxy)benzoyl)benzoic acid, processes for their preparation and their use as spasmolytic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-04-25 | — | — | EP | disclosed |
| EP-0364941-A1 | Branched-chain alkyl esters of 2-(4-(2-piperidino ethoxy)benzoyl)benzoic acid, processes for their preparation and their use as spasmolytic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-04-25 | — | — | EP | disclosed |