Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | SELP | P16109 | 2/20 | 0.34 |
| ▸ | SELE | P16581 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7215007 | 0.91 | SPHK1 (0.42) | SPHK1HDAC1HPGDCHRM2CHRM4 | |
| SCHEMBL7215002 | 0.91 | SPHK1 (0.42) | SPHK1HDAC1HPGDCHRM2CHRM4 | |
| SCHEMBL7218632 | 0.66 | SPHK1 (0.46) | SPHK1HPGDKDM4EALDH1A1RAB9A | |
| SCHEMBL7219294 | 0.65 | HPGD (0.45) | HDAC1HPGDKDM4EALDH1A1RAB9A | |
| SCHEMBL7219298 | 0.65 | HPGD (0.45) | HDAC1HPGDKDM4EALDH1A1RAB9A | |
| SCHEMBL7214906 | 0.65 | ALDH1A1 (0.57) | SPHK1HPGDCHRM2CHRM4CHRM5 | |
| SCHEMBL7214955 | 0.64 | MAPT (0.55) | SPHK1HPGDCHRM2CHRM4CHRM5 | |
| SCHEMBL1856548 | 0.64 | ALDH1A1 (0.56) | SPHK1HPGDCHRM2CHRM4CHRM5 | |
| SCHEMBL1312815 | 0.64 | ALDH1A1 (0.56) | SPHK1HPGDCHRM2CHRM4CHRM5 | |
| SCHEMBL1858866 | 0.64 | ALDH1A1 (0.56) | SPHK1HPGDCHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998037068-A1 | BENZOIC ACID DERIVATIVES AND RELATED COMPOUNDS AS ANTIARRHYTHMIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-08-27 | — | — | WO | disclosed |