Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21689981 | 0.82 | ACACB (0.56) | HRH3SMN1; SMN2HTTNPC1RAB9A | |
| SCHEMBL27041590 | 0.81 | ACE (0.55) | KMT2AKCNJ1MAPK1 | |
| SCHEMBL27041599 | 0.81 | ACE (0.55) | KMT2AKCNJ1MAPK1 | |
| SCHEMBL7555443 | 0.80 | HRH3 (0.56) | HIF1AEPAS1HRH3SMN1; SMN2HTT | |
| SCHEMBL7555448 | 0.80 | HRH3 (0.56) | HIF1AEPAS1HRH3SMN1; SMN2HTT | |
| SCHEMBL21690039 | 0.79 | KMT2A (0.57) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL21690109 | 0.79 | KMT2A (0.57) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL23194179 | 0.78 | CACNA1B (0.45) | SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL21690040 | 0.77 | FKBP1A (0.65) | SMN1; SMN2HTTNPC1RAB9AALDH1A1 | |
| SCHEMBL27848477 | 0.76 | HRH3 (0.55) | HIF1AEPAS1HRH3SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0683792-A4 | LHRH ANTAGONISTS HAVING MODIFIED AMINOACYL RESIDUES AT POSTIONS 5 AND 6. | ABBOTT LAB (US) | 1998-11-18 | — | — | EP | disclosed |
| EP-0683792-A1 | LHRH ANTAGONISTS HAVING MODIFIED AMINOACYL RESIDUES AT POSTIONS 5 AND 6 | ABBOTT LABORATORIES (US) | 1995-11-29 | — | — | EP | disclosed |
| WO-1994014841-A1 | LHRH ANTAGONISTS HAVING MODIFIED AMINOACYL RESIDUES AT POSTIONS 5 AND 6 | ABBOTT LABORATORIES (US) | 1994-07-07 | — | — | WO | disclosed |