Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.56 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.54 |
| ▸ | NOS3 | P29474 | 1/20 | 0.54 |
| ▸ | NOS1 | P29475 | 1/20 | 0.54 |
| ▸ | NOS2 | P35228 | 1/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | XIAP | P98170 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.52 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7555448 | 1.00 | HRH3 (0.56) | HRH3SLC7A5NOS3NOS1NOS2 | |
| SCHEMBL31754288 | 0.88 | SLC7A5 (0.57) | HRH3SLC7A5ALPIPKMPTGS1 | |
| SCHEMBL6753271 | 0.85 | SLC7A5 (0.54) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL28706525 | 0.85 | SLC7A5 (0.54) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL5024981 | 0.85 | SLC7A5 (0.54) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL7410961 | 0.81 | ACACB (0.56) | HRH3SLC7A5HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL8711587 | 0.80 | HIF1A (0.51) | HRH3AOC3HTTHPGDHIF1A | |
| SCHEMBL19234910 | 0.80 | LMNA (0.48) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL19234914 | 0.80 | LMNA (0.48) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL19234896 | 0.80 | KDM4E (0.62) | HPGDSMN1; SMN2ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260001914-A1 | MACROCYCLIC PEPTIDES TARGETING KRAS | MERCK SHARP & DOHME LLC (US) | 2026-01-01 | — | — | US | disclosed |
| CN-1136915-C | Use of nona- and decapeptides in the preparation of a drug for the treatment of aids | �����ɷ� | 2004-02-04 | — | — | CN | disclosed |
| EP-0703786-B1 | USE OF NONA- AND DECAPEPTIDES IN THE PREPARATION OF A DRUG FOR THE TREATMENT OF AIDS | ZENTARIS AG (DE) | 2002-02-13 | — | — | EP | disclosed |
| US-5985834-A | LHRH-ANTAGONISTIC AND BOMBESIN-ANTAGONISTIC NONA- AND DECAPEPTIDES SUITABLE FOR USE IN PREPARATION OF DRUG FOR TREATMENT OF AIDS AND ARC (AIDS RELATED COMPLEX) AS WELL AS FOR USE IN PREPARATION OF IMMUNOSTIMULATION DRUG | ASTA MEDICA AG (DE) | 1999-11-16 | — | — | US | disclosed |
| CN-1125400-A | Use of nona- and decapeptides in the preparation of a drug for the treatment of aids | ASTA MEDICA AG (DE) | 1996-06-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260001914-A1 | MACROCYCLIC PEPTIDES TARGETING KRAS | KRAS, NRAS, HRAS | HRH3 381/4885SLC7A5 308/4885NOS3 4323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.