Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 7/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7125071 | 0.83 | MAOA (0.61) | PTGS1PTGS2BCHEADRA2AADRA2B | |
| SCHEMBL8715308 | 0.81 | PTGS1 (0.46) | PTGS1PTGS2BCHEADRA2AADRA2B | |
| SCHEMBL30184394 | 0.80 | MAOA (0.58) | PTGS1PTGS2BCHEADRA2AADRA2B | |
| SCHEMBL627482 | 0.80 | MAOA (0.58) | PTGS1PTGS2BCHEADRA2AADRA2B | |
| SCHEMBL10052735 | 0.79 | CYP2D6 (0.72) | PTGS1PTGS2BCHEADRA2AADRA2B | |
| SCHEMBL25842306 | 0.78 | KDM1A (0.48) | PTGS1PTGS2ADRA2AADRA2BADRA2C | |
| SCHEMBL8714035 | 0.76 | KDM1A (0.56) | ADRA2AADRA2BADRA2CCHRM3SLC6A2 | |
| SCHEMBL28045484 | 0.75 | NOX1 (0.59) | PTGS2BCHEADRA2AADRA2BADRA2C | |
| SCHEMBL20760007 | 0.74 | NOX1 (0.46) | ADRA2AADRA2BADRA2CCHRM3SLC6A2 | |
| SCHEMBL8711321 | 0.73 | BCHE (0.41) | PTGS1PTGS2BCHEADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830902-A | SQUALENE SYNTHASE INHIBITOR | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-11-03 | — | — | US | disclosed |
| CN-1177353-A | Novel quinuclidine derivatives having tricyclic fused hereto ring | YAMANOUCHI PHARMA CO LTD (JP) | 1998-03-25 | — | — | CN | disclosed |
| EP-0812840-A1 | NOVEL QUINUCLIDINE DERIVATIVES HAVING TRICYCLIC FUSED HETERO RING | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-12-17 | — | — | EP | disclosed |