Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 3/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD1 | P21728 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | PRNP | P04156 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16492910 | 0.84 | NOX1 (0.83) | NOX1LMNAMAPTMAPK1TDP1 | |
| SCHEMBL27840689 | 0.80 | LMNA (0.59) | NOX1LMNAMAPTMAPK1TDP1 | |
| SCHEMBL627482 | 0.79 | MAOA (0.58) | NOX1LMNAMAPTMAPK1TDP1 | |
| SCHEMBL30184394 | 0.79 | MAOA (0.58) | NOX1LMNAMAPTMAPK1TDP1 | |
| SCHEMBL27913832 | 0.78 | LMNA (0.61) | NOX1LMNAMAPTMAPK1TDP1 | |
| SCHEMBL10370775 | 0.76 | HTR1A (0.58) | NOX1LMNAMAPTMAPK1TDP1 | |
| SCHEMBL8711321 | 0.75 | BCHE (0.41) | NOX1LMNAMAPTMAPK1L3MBTL1 | |
| SCHEMBL8711615 | 0.75 | PTGS1 (0.45) | NOX1LMNAMAPTMAPK1L3MBTL1 | |
| SCHEMBL28045616 | 0.75 | HTR1A (0.64) | NOX1LMNAMAPTMAPK1TDP1 | |
| SCHEMBL1983443 | 0.75 | NOX1 (1.00) | NOX1LMNAMAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105218480-A | A kind of 1-(N-alkyl phenothiazinyl)-1-methyl (H)-2-replaces the preparation method of Schiff | UNIV SHAANXI SCIENCE & TECH | 2016-01-06 | — | — | CN | disclosed |