Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 5/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10916062 | 0.69 | CHRNB2 (0.58) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| SCHEMBL3206683 | 0.69 | CHRNB2 (0.58) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| SCHEMBL3217847 | 0.69 | CHRNB2 (0.58) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| Hydrochloric Acid SCHEMBL10913507 | 0.68 | CHRNB2 (0.57) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| Hydrochloric Acid SCHEMBL10913504 | 0.68 | CHRNB2 (0.57) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| SCHEMBL4278182 | 0.68 | CHRNB2 (0.70) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| SCHEMBL4278185 | 0.68 | CHRNB2 (0.70) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| SCHEMBL9217892 | 0.68 | CHRNB2 (0.70) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| SCHEMBL9217890 | 0.68 | CHRNB2 (0.70) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| SCHEMBL10916010 | 0.67 | CHRNB2 (0.44) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830902-A | SQUALENE SYNTHASE INHIBITOR | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-11-03 | — | — | US | disclosed |
| EP-0812840-A1 | NOVEL QUINUCLIDINE DERIVATIVES HAVING TRICYCLIC FUSED HETERO RING | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-12-17 | — | — | EP | disclosed |