Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 5/20 | 0.70 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.70 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217892 | 1.00 | CHRNB2 (0.70) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| SCHEMBL4278182 | 0.84 | CHRNB2 (0.70) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| SCHEMBL4278185 | 0.84 | CHRNB2 (0.70) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| SCHEMBL8713166 | 0.82 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| Hydrochloric Acid SCHEMBL2422984 | 0.82 | CHRNB2 (0.68) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| Hydrochloric Acid SCHEMBL2421934 | 0.82 | CHRNB2 (0.68) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| SCHEMBL8713172 | 0.82 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| SCHEMBL8713445 | 0.82 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| SCHEMBL12614211 | 0.78 | CHRNB2 (0.67) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| SCHEMBL7490432 | 0.78 | CHRNB2 (0.62) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414394-B1 | Azabicyclic Derivatives having muscarinic receptor affinity | BEECHAM GROUP PLC (GB) | 1995-07-05 | — | — | EP | disclosed |
| EP-0414394-A2 | Azabicyclic Derivatives having muscarinic receptor affinity | BEECHAM GROUP PLC (GB) | 1991-02-27 | — | — | EP | disclosed |