Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8711742 | 0.81 | ACHE (0.32) | ACHETSHR | |
| SCHEMBL7716022 | 0.73 | TSHR (0.39) | ACHETSHR | |
| SCHEMBL7718937 | 0.71 | ACHE (0.36) | ACHETSHR | |
| SCHEMBL7717188 | 0.70 | TSHR (0.35) | ACHETSHR | |
| SCHEMBL7718842 | 0.65 | ACHE (0.31) | ACHE | |
| SCHEMBL9022468 | 0.64 | KMT2A (0.37) | ACHETSHR | |
| SCHEMBL30045058 | 0.64 | POLB (0.35) | ACHETSHR | |
| SCHEMBL5105445 | 0.63 | TSHR (0.46) | ACHETSHR | |
| SCHEMBL7715865 | 0.61 | ACHE (0.39) | ACHETSHR | |
| SCHEMBL353227 | 0.61 | POLB (0.38) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0642518-B1 | PHOSPHONOSULFONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMA (US) | 1998-08-05 | — | — | EP | disclosed |
| US-5731299-A | OSTEOPOROSIS; RHEUMATOID ARTHRITIS | THE PROCTER & GAMBLE COMPANY (US) | 1998-03-24 | — | — | US | disclosed |
| EP-0642518-A1 | PHOSPHONOSULFONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMACEUTICALS (US) | 1995-03-15 | — | — | EP | disclosed |
| WO-1993024495-A1 | PHOSPHONOSULFONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1993-12-09 | — | — | WO | disclosed |