SCHEMBL8707828

SCHEMBL8707828

C=CC(Cl)(CCCCC)OCc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CETP P11597 3/20 0.39
MBOAT4 Q96T53 1/20 0.39
TSHR P16473 2/20 0.35
MAPK1 P28482 2/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
SIGMAR1 Q99720 2/20 0.35
GAA P10253 1/20 0.35
EBP Q15125 1/20 0.34
BCHE P06276 1/20 0.34
ACHE P22303 1/20 0.34
DNM1 Q05193 1/20 0.34
MEN1 O00255 1/20 0.33
TP53 P04637 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
EPHX2 P34913 1/20 0.33
PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6811521 0.82 CETP (0.39) CETPMBOAT4TSHRMAPK1ALDH1A1
SCHEMBL8709144 0.81 CETP (0.41) CETPMBOAT4MAPK1SIGMAR1EBP
SCHEMBL6811511 0.81 MBOAT4 (0.43) CETPMBOAT4TSHRMAPK1ALDH1A1
SCHEMBL8709296 0.79 MBOAT4 (0.45) CETPMBOAT4TSHRMAPK1ALDH1A1
SCHEMBL1614849 0.76 CETP (0.47) CETPMBOAT4TSHRMAPK1ALDH1A1
SCHEMBL9116193 0.76 CETP (0.44) CETPMBOAT4TSHRMAPK1ALDH1A1
SCHEMBL1614607 0.76 CETP (0.47) CETPMBOAT4TSHRMAPK1ALDH1A1
SCHEMBL10389226 0.76 CETP (0.44) CETPMBOAT4TSHRMAPK1ALDH1A1
SCHEMBL9221499 0.74 CETP (0.43) CETPMBOAT4TSHRMAPK1ALDH1A1
Ammonia Solution, Strong SCHEMBL11029622 0.74 MMP1 (0.37) MBOAT4MAPK1ALDH1A1CYP3A4SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5731395-A POLYMER CONTAINING DIVINYLBENZENE AND STYRENE COMPOUND ARAKAWA CHEMICAL INDUSTRIES, LTD. (JP) 1998-03-24 US disclosed