Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | MDH1 | P40925 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8707948 | 0.95 | ADRA2A (0.44) | KCNH2ADRA2AADORA3CHRM1MAOA | |
| SCHEMBL8709047 | 0.91 | ADRA2A (0.47) | KCNH2ADRA2AADORA3CHRM1MAOA | |
| Hydrochloric Acid SCHEMBL7869803 | 0.91 | ADRA2A (0.43) | KCNH2ADRA2AADORA3CHRM1MAOA | |
| SCHEMBL8709099 | 0.88 | ADRA2A (0.49) | KCNH2ADRA2AADORA3CHRM1MAOA | |
| SCHEMBL8708307 | 0.87 | ADRA2A (0.48) | KCNH2ADRA2AADORA3CHRM1MAOA | |
| SCHEMBL8712141 | 0.86 | ADRA2A (0.45) | KCNH2ADRA2AADORA3CHRM1MAOA | |
| SCHEMBL8711424 | 0.86 | ADRA2A (0.47) | KCNH2ADRA2AADORA3CHRM1MAOA | |
| SCHEMBL8708504 | 0.84 | ALDH1A1 (0.46) | KCNH2ADRA2AADORA3CHRM1MAOA | |
| SCHEMBL8711082 | 0.84 | ADRA2A (0.46) | KCNH2ADRA2AADORA3CHRM1MAOA | |
| SCHEMBL8712026 | 0.84 | POLB (0.46) | KCNH2ADRA2AADORA3CHRM1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998054140-A1 | NOVEL TEREPHTHALAMIDE DERIVATIVES | DONGWHA PHARMACEUTICAL IND. CO., LTD. (KR) | 1998-12-03 | — | — | WO | disclosed |