Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | CPB1 | P15086 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 3/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.37 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538284 | 0.91 | LMNA (0.43) | LMNAKMT2APOLBLGALS8CPB1 | |
| SCHEMBL8538288 | 0.91 | LMNA (0.43) | LMNAKMT2APOLBLGALS8CPB1 | |
| SCHEMBL11322341 | 0.89 | LMNA (0.58) | LMNAKMT2APOLBLGALS8MMP9 | |
| SCHEMBL11322337 | 0.86 | LMNA (0.54) | LMNAKMT2APOLBLGALS8MMP9 | |
| SCHEMBL11325557 | 0.86 | LMNA (0.54) | LMNAKMT2APOLBLGALS8MMP9 | |
| SCHEMBL2007087 | 0.83 | LMNA (0.76) | LMNAKMT2APOLBMMP12ALDH1A1 | |
| SCHEMBL2007088 | 0.83 | LMNA (0.76) | LMNAKMT2APOLBMMP12ALDH1A1 | |
| SCHEMBL12837317 | 0.83 | LMNA (0.76) | LMNAKMT2APOLBMMP12ALDH1A1 | |
| SCHEMBL12812848 | 0.82 | POLB (0.41) | LMNAKMT2APOLBALDH1A1 | |
| SCHEMBL12812846 | 0.82 | POLB (0.41) | LMNAKMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849709-A | Saccharopeptides and derivatives thereof | GLYCOMED INCORPORATED (US) | 1998-12-15 | — | — | US | disclosed |