Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18379267 | 0.76 | SMN1; SMN2 (0.49) | SMN1; SMN2L3MBTL1HTTCYP2D6POLB | |
| SCHEMBL14565210 | 0.76 | SMN1; SMN2 (0.49) | SMN1; SMN2L3MBTL1HTTCYP2D6POLB | |
| SCHEMBL9225828 | 0.74 | SMN1; SMN2 (0.43) | SMN1; SMN2L3MBTL1HTTCYP2D6POLB | |
| SCHEMBL31470602 | 0.66 | INPP5A (0.41) | SMN1; SMN2CHRM1CHRM3MEN1KMT2A | |
| SCHEMBL22479228 | 0.66 | INPP5A (0.41) | SMN1; SMN2CHRM1CHRM3MEN1KMT2A | |
| SCHEMBL28725576 | 0.65 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1HTTCYP2D6POLB | |
| SCHEMBL23175194 | 0.65 | SMN1; SMN2 (0.46) | SMN1; SMN2L3MBTL1HTTCYP2D6POLB | |
| SCHEMBL3749371 | 0.65 | SMN1; SMN2 (0.46) | SMN1; SMN2L3MBTL1HTTCYP2D6POLB | |
| SCHEMBL23160556 | 0.65 | INPP5A (0.40) | SMN1; SMN2L3MBTL1HTTCYP2D6CHRM1 | |
| SCHEMBL23160555 | 0.65 | INPP5A (0.40) | SMN1; SMN2L3MBTL1HTTCYP2D6CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0642518-B1 | PHOSPHONOSULFONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMA (US) | 1998-08-05 | — | — | EP | disclosed |