Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712234 | 1.00 | RAB9A (0.49) | RAB9AKMT2ANPC1MEN1L3MBTL1 | |
| SCHEMBL18512240 | 0.83 | TDP1 (0.48) | RAB9AKMT2ANPC1MEN1L3MBTL1 | |
| SCHEMBL9053232 | 0.81 | ALDH1A1 (0.52) | RAB9AKMT2ANPC1MEN1L3MBTL1 | |
| SCHEMBL9053235 | 0.81 | ALDH1A1 (0.52) | RAB9AKMT2ANPC1MEN1L3MBTL1 | |
| SCHEMBL3212540 | 0.79 | KMT2A (0.45) | RAB9AKMT2ANPC1MEN1L3MBTL1 | |
| SCHEMBL3212537 | 0.79 | KMT2A (0.45) | RAB9AKMT2ANPC1MEN1L3MBTL1 | |
| SCHEMBL12215821 | 0.78 | ALDH1A1 (0.41) | RAB9AKMT2ANPC1MEN1L3MBTL1 | |
| SCHEMBL2522391 | 0.78 | ALDH1A1 (0.41) | RAB9AKMT2ANPC1MEN1L3MBTL1 | |
| SCHEMBL2522389 | 0.78 | ALDH1A1 (0.41) | RAB9AKMT2ANPC1MEN1L3MBTL1 | |
| SCHEMBL21685492 | 0.78 | MAPT (0.44) | RAB9AKMT2ANPC1MEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998004532-A1 | FUNGICIDAL ARYL-SUBSTITUTED FIVE-MEMBERED HETEROCYLIC COMPOUNDS | AGREVO UK LIMITED (GB) | 1998-02-05 | — | — | WO | disclosed |