Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712260 | 0.80 | TP53 (0.42) | TP53 | |
| SCHEMBL29224741 | 0.78 | CTSA (0.31) | — | |
| SCHEMBL24725871 | 0.73 | TP53 (0.36) | TP53 | |
| SCHEMBL21224308 | 0.70 | PEPD (0.39) | TP53 | |
| SCHEMBL36130 | 0.69 | TP53 (0.42) | TP53 | |
| SCHEMBL28336541 | 0.68 | PEPD (0.38) | TP53 | |
| SCHEMBL27881916 | 0.67 | TP53 (0.40) | TP53 | |
| SCHEMBL225761 | 0.67 | — | — | |
| SCHEMBL6296205 | 0.67 | — | — | |
| Methylmalonic Acid SCHEMBL28405076 | 0.66 | TP53 (0.44) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4557934-A | ALONG WITH A DIOL PYRROLIDONE OR AN AZACYCLOPENTAN-2-ONE | THE PROCTER & GAMBLE COMPANY (US) | 1985-12-10 | — | — | US | claimed |
| EP-0129285-B1 | PENETRATING TOPICAL PHARMACEUTICAL COMPOSITIONS CONTAINING N-(2-HYDROXYETHYL)PYRROLIDONE | THE PROCTER & GAMBLE COMPANY (US) | 1991-05-15 | — | — | EP | disclosed |
| EP-0055239-B1 | NOVEL DERIVATIVES OF GUANINE | Astra Läkemedel Aktiebolag (SE) | 1986-07-16 | — | — | EP | disclosed |
| EP-0103552-B1 | NOVEL DERIVATIVES OF GUANINE | Astra Läkemedel Aktiebolag (SE) | 1986-05-07 | — | — | EP | disclosed |
| EP-0103551-B1 | NOVEL DERIVATIVES OF GUANINE | Astra Läkemedel Aktiebolag (SE) | 1986-02-26 | — | — | EP | disclosed |
| US-4557934-A | ALONG WITH A DIOL PYRROLIDONE OR AN AZACYCLOPENTAN-2-ONE | THE PROCTER & GAMBLE COMPANY (US) | 1985-12-10 | — | — | US | disclosed |
| US-4537776-A | PERCUTANEOUS DELIVERY OF ANTIINFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1985-08-27 | — | — | US | disclosed |
| US-4495190-A | VIRICIDES; ANTITUMOR AND ANTICARCINOGENIC AGENTS | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1985-01-22 | — | — | US | disclosed |
| EP-0129285-A2 | Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl)pyrrolidone | THE PROCTER & GAMBLE COMPANY (US) | 1984-12-27 | — | — | EP | disclosed |
| EP-0129284-A2 | Improved penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one | THE PROCTER & GAMBLE COMPANY (US) | 1984-12-27 | — | — | EP | disclosed |
| EP-0112364-A1 | NOVEL DERIVATIVES OF GUANINE II | Astra Läkemedel Aktiebolag (SE) | 1984-07-04 | — | — | EP | disclosed |
| EP-0112353-A1 | NOVEL DERIVATIVES OF GUANINE I | Astra Läkemedel Aktiebolag (SE) | 1984-07-04 | — | — | EP | disclosed |
| EP-0103552-A2 | Novel derivatives of guanine | Astra Läkemedel Aktiebolag (SE) | 1984-03-21 | — | — | EP | disclosed |
| EP-0103551-A2 | Novel derivatives of guanine | Astra Läkemedel Aktiebolag (SE) | 1984-03-21 | — | — | EP | disclosed |
| WO-1984000168-A1 | NOVEL DERIVATIVES OF GUANINE II | ASTRA LAEKEMEDEL AB (SE) | 1984-01-19 | — | — | WO | disclosed |
| WO-1984000167-A1 | NOVEL DERIVATIVES OF GUANINE I | ASTRA LAEKEMEDEL AB (SE) | 1984-01-19 | — | — | WO | disclosed |
| EP-0095813-A2 | Penetrating topical pharmaceutical compositions containing 9-(2-hydroxyethoxymethyl) guanine | THE PROCTER & GAMBLE COMPANY (US) | 1983-12-07 | — | — | EP | disclosed |
| WO-1982002202-A1 | NOVEL DERIVATIVES OF GUANINE | ASTRA LAEKEMEDEL AB (SE) | 1982-07-08 | — | — | WO | disclosed |
| EP-0055239-A1 | Novel derivatives of guanine | Astra Läkemedel Aktiebolag (SE) | 1982-06-30 | — | — | EP | disclosed |