Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24858793 | 0.86 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1CA14 | |
| SCHEMBL8712260 | 0.86 | TP53 (0.42) | TP53KMT2ASMN1; SMN2SLC7A5 | |
| SCHEMBL3803538 | 0.79 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2ALDH1A1CA14 | |
| SCHEMBL225761 | 0.78 | — | — | |
| SCHEMBL686682 | 0.75 | — | — | |
| SCHEMBL36130 | 0.75 | TP53 (0.42) | TP53SMN1; SMN2SLC7A5 | |
| SCHEMBL11420619 | 0.74 | SMN1; SMN2 (0.42) | TP53KMT2ASMN1; SMN2ALDH1A1SLC1A3 | |
| SCHEMBL9806941 | 0.73 | TP53 (0.32) | TP53 | |
| SCHEMBL24240716 | 0.72 | — | — | |
| SCHEMBL6296205 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220389424-A1 | MODIFIED DOUBLE-STRANDED RNA AGENTS | BANK OF AMERICA, N.A. | 2022-12-08 | — | — | US | disclosed |
| US-20170275626-A1 | MODIFIED DOUBLE-STRANDED RNA AGENTS | BANK OF AMERICA, N.A. | 2017-09-28 | — | — | US | disclosed |