Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL381848 | 0.90 | PDE3A (0.41) | POLA1PDE4DPDE3ASLC29A1LMNA | |
| SCHEMBL8716120 | 0.76 | POLA1 (0.40) | POLA1PDE4DPDE3ASLC29A1LMNA | |
| SCHEMBL12813023 | 0.76 | DNMT1 (0.41) | LMNAMTOR | |
| SCHEMBL6534202 | 0.74 | PDE3A (0.45) | POLA1PDE4DPDE3ASLC29A1LMNA | |
| SCHEMBL27321202 | 0.73 | PDE3A (0.44) | POLA1PDE4DPDE3ASLC29A1LMNA | |
| SCHEMBL29414447 | 0.73 | PDE3A (0.42) | POLA1PDE4DPDE3ASLC29A1LMNA | |
| SCHEMBL31189348 | 0.72 | PDE3A (0.48) | POLA1PDE4DPDE3ASLC29A1LMNA | |
| SCHEMBL6060293 | 0.71 | PDE3A (0.35) | POLA1PDE4DPDE3ASLC29A1LMNA | |
| SCHEMBL11664470 | 0.70 | LMNA (0.46) | POLA1PDE4DPDE3ASLC29A1LMNA | |
| SCHEMBL60518 | 0.69 | SLC28A1 (0.39) | SLC29A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0698610-B1 | PROCESS FOR PRODUCING SIALIC ACID DERIVATIVE AND NOVEL SIALIC ACID DERIVATIVE | JAPAN TOBACCO INC (JP) | 1998-08-12 | — | — | EP | disclosed |
| US-5621086-A | Sialic acid derivative and method of manufacturing it | JAPAN TOBACCO INC. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0698610-A1 | PROCESS FOR PRODUCING SIALIC ACID DERIVATIVE AND NOVEL SIALIC ACID DERIVATIVE | Japan Tobacco Inc. (JP) | 1996-02-28 | — | — | EP | disclosed |