Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8086673 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL812403 | 0.65 | SMN1; SMN2 (0.43) | ALDH1A1KMT2APOLBKDM4EHPGD | |
| SCHEMBL4433341 | 0.63 | GAA (0.40) | ALDH1A1MEN1KMT2APOLBKDM4E | |
| SCHEMBL5771881 | 0.62 | MAPT (0.33) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL14612064 | 0.62 | — | — | |
| SCHEMBL6207998 | 0.61 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL12213145 | 0.61 | — | — | |
| SCHEMBL10045608 | 0.60 | — | — | |
| SCHEMBL16592250 | 0.59 | PARP15 (0.30) | — | |
| SCHEMBL13475987 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807805-A | Substituted thiophene derivatives as pesticides and herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-09-15 | — | — | US | disclosed |