Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.34 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7098248 | 0.86 | ELANE (0.36) | SMN1; SMN2KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL6207995 | 0.72 | PGR (0.40) | SMN1; SMN2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL812401 | 0.72 | PGR (0.40) | SMN1; SMN2ALDH1A1TNKS2GAABRPF1 | |
| SCHEMBL8650400 | 0.72 | GAA (0.54) | SMN1; SMN2KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL10814471 | 0.66 | GPR119 (0.42) | SMN1; SMN2KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL9126229 | 0.65 | DPP4 (0.41) | SMN1; SMN2KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL4433341 | 0.65 | GAA (0.40) | KDM4EALDH1A1HPGDGAAPOLB | |
| SCHEMBL8712306 | 0.65 | ALDH1A1 (0.41) | SMN1; SMN2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6207998 | 0.64 | ALDH1A1 (0.49) | SMN1; SMN2KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL671133 | 0.63 | CYP2A6 (0.67) | SMN1; SMN2KDM4EALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8058210-B2 | Arylphenyl-substituted cyclic keto-enols | BAYER CROPSCIENCE AG (DE) | 2011-11-15 | — | — | US | disclosed |
| US-7718706-B2 | Arylphenyl-substituted cyclic keto-enols | BAYER AKTIENGESELLSCHAFT (DE) | 2010-05-18 | — | — | US | disclosed |
| US-20100087320-A1 | ARYLPHENYL-SUBSTITUTED CYCLIC KETO-ENOLS | LIEB FOLKER | 2010-04-08 | — | — | US | disclosed |
| US-20080081807-A1 | Arylphenyl-substituted cyclic keto-enols | LIEB FOLKER | 2008-04-03 | — | — | US | disclosed |
| US-7288676-B2 | Arylphenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-10-30 | — | — | US | disclosed |
| US-7105471-B2 | Arylphenyl-substituted cyclic ketoenols | BAYER AKTIENGESELLSCHAFT (DE) | 2006-09-12 | — | — | US | disclosed |
| US-20060122061-A1 | Arylphenyl-substituted cyclic ketoenols | LIEB FOLKER | 2006-06-08 | — | — | US | disclosed |
| US-6806264-B2 | PESTICIDES AND HERBICIDES; WOOD PROTECTANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-10-19 | — | — | US | disclosed |
| US-20040127365-A1 | Arylphenyl-substituted cyclic ketoenols | LIEB FOLKER (DE) | 2004-07-01 | — | — | US | disclosed |
| US-6716832-B2 | PESTICIDES AND HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-04-06 | — | — | US | disclosed |
| US-6693092-B2 | HERBICIDES; PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-02-17 | — | — | US | disclosed |
| US-20030073851-A1 | Arylphenyl-substituted cyclic ketoenols | LIEB FOLKER (DE) | 2003-04-17 | — | — | US | disclosed |
| US-20020188136-A1 | Arylphenyl-substituted cyclic ketoenols | LIEB FOLKER (DE) | 2002-12-12 | — | — | US | disclosed |
| US-6458965-B1 | HERBICIDES, ANTIGROWTH AGENTS AND SURFACTANTS FOR WOOD PRESERVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-01 | — | — | US | disclosed |
| US-6417370-B1 | HERBICIDES, PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122061-A1 | Arylphenyl-substituted cyclic ketoenols | KCNE1, KCNQ3, KCNQ2 | SMN1; SMN2 4743/4885KDM4E 98/4885ALDH1A1 2523/4885 |
| US-20030073851-A1 | Arylphenyl-substituted cyclic ketoenols | KCNE1, CYP2E1, CYP21A2 | SMN1; SMN2 4667/4885KDM4E 148/4885ALDH1A1 1797/4885 |
| US-20080081807-A1 | Arylphenyl-substituted cyclic keto-enols | KCNE1, DDT, KCNQ3 | SMN1; SMN2 4753/4885KDM4E 81/4885ALDH1A1 2569/4885 |
| US-20100087320-A1 | ARYLPHENYL-SUBSTITUTED CYCLIC KETO-ENOLS | KCNE1, DDT, KCNQ3 | SMN1; SMN2 4753/4885KDM4E 81/4885ALDH1A1 2569/4885 |
| US-20040127365-A1 | Arylphenyl-substituted cyclic ketoenols | KCNE1, CYP2E1, CYP21A2 | SMN1; SMN2 4667/4885KDM4E 148/4885ALDH1A1 1797/4885 |
| US-20020188136-A1 | Arylphenyl-substituted cyclic ketoenols | KCNE1, CYP21A2, KCNQ3 | SMN1; SMN2 4649/4885KDM4E 144/4885ALDH1A1 1648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.