SCHEMBL8712481

SCHEMBL8712481

CC(=S)Sc1ccc(C(=O)O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
TP53 P04637 1/20 0.50
ALDH1A1 P00352 5/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
SRD5A2 P31213 2/20 0.44
HTT P42858 1/20 0.44
HPGD P15428 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
LMNA P02545 1/20 0.43
CA1 P00915 3/20 0.43
CA2 P00918 3/20 0.43
CA12 O43570 1/20 0.43
CA3 P07451 1/20 0.43
TYR P14679 1/20 0.43
DRD1 P21728 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA5A P35218 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5434976 0.83 TSHR (0.55) TSHRTP53ALDH1A1SMN1; SMN2SRD5A2
SCHEMBL4275274 0.79 TSHR (0.44) TSHRTP53ALDH1A1SMN1; SMN2SRD5A2
SCHEMBL8712403 0.78 TSHR (0.60) TSHRTP53ALDH1A1SMN1; SMN2SRD5A2
SCHEMBL8715668 0.77 HSD17B10 (0.61) TSHRALDH1A1HPGDL3MBTL1LMNA
SCHEMBL9134567 0.75 TSHR (0.63) TSHRTP53ALDH1A1SMN1; SMN2SRD5A2
SCHEMBL2374205 0.75 MAPT (0.41) ALDH1A1SMN1; SMN2HTTHPGDLMNA
Terephthalic Acid SCHEMBL28368940 0.74 TSHR (0.71) TSHRTP53ALDH1A1SMN1; SMN2SRD5A2
Terephthalic Acid SCHEMBL28368939 0.74 TSHR (0.71) TSHRTP53ALDH1A1SMN1; SMN2SRD5A2
Terephthalic Acid SCHEMBL123278 0.74 TSHR (0.80) TSHRTP53ALDH1A1SMN1; SMN2SRD5A2
Terephthalic Acid SCHEMBL28358071 0.74 TSHR (0.80) TSHRTP53ALDH1A1SMN1; SMN2SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5847061-A Process for producing polymers having terminal functional group which may be protected KURARAY CO., LTD. (JP) 1998-12-08 US disclosed
EP-0704460-B1 PROCESS FOR PRODUCING POLYMER TERMINATED WITH OPTIONALLY PROTECTED FUNCTIONAL GROUP KURARAY CO (JP) 1998-11-04 EP disclosed
EP-0704460-A1 PROCESS FOR PRODUCING POLYMER TERMINATED WITH OPTIONALLY PROTECTED FUNCTIONAL GROUP KURARAY CO., LTD. (JP) 1996-04-03 EP disclosed