Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.60 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 2/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30908830 | 0.89 | SLC6A4 (0.58) | ADRA1DKDM4EATMBRD4ALDH1A1 | |
| SCHEMBL807343 | 0.81 | HTR2C (0.74) | ADRA1DKDM4EATMBRD4ALDH1A1 | |
| SCHEMBL734917 | 0.81 | HTR2C (0.79) | ADRA1DKDM4EATMBRD4ALDH1A1 | |
| SCHEMBL2910862 | 0.79 | HTR2C (0.72) | ADRA1DKDM4EATMBRD4ALDH1A1 | |
| SCHEMBL28594057 | 0.77 | HTR2C (0.74) | ADRA1DKDM4EATMBRD4ALDH1A1 | |
| SCHEMBL1570520 | 0.77 | KDM4E (0.64) | ADRA1DKDM4EATMBRD4ALDH1A1 | |
| SCHEMBL3256692 | 0.77 | KDM4E (0.83) | ADRA1DKDM4EATMBRD4ALDH1A1 | |
| SCHEMBL30415306 | 0.77 | KDM4E (0.83) | ADRA1DKDM4EATMBRD4ALDH1A1 | |
| SCHEMBL16801497 | 0.77 | KDM4E (0.64) | ADRA1DKDM4EATMBRD4ALDH1A1 | |
| SCHEMBL18324797 | 0.76 | ADRA1D (0.60) | ADRA1DKDM4EATMBRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0875513-A1 | Substituted heteroaromatic 5-HT 1F agonists | ELI LILLY AND COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |
| WO-1998046570-A1 | SUBSTITUTED HETEROAROMATIC 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |