SCHEMBL8712642

SCHEMBL8712642

CCN(CCCl)c1ccccc1C=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
LMNA P02545 2/20 0.39
BLM P54132 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
THRB P10828 1/20 0.39
ALDH1A3 P47895 3/20 0.38
ALDH1A1 P00352 7/20 0.38
ALDH3A1 P30838 3/20 0.38
MAPT P10636 4/20 0.37
TSHR P16473 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
NFKB1 P19838 1/20 0.37
CYP2C19 P33261 1/20 0.37
HSD17B10 Q99714 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
HTT P42858 2/20 0.34
HPGD P15428 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9386169 0.90 KMT2A (0.44) MEN1KMT2ALMNABLMTDP1
SCHEMBL29354732 0.88 KMT2A (0.50) MEN1KMT2ALMNABLMTDP1
SCHEMBL465195 0.88 KMT2A (0.50) MEN1KMT2ALMNABLMTDP1
SCHEMBL7029449 0.83 MEN1 (0.40) MEN1KMT2ALMNABLMTDP1
Biphenyl SCHEMBL61055 0.81 MEN1 (0.43) MEN1KMT2ALMNABLMTDP1
SCHEMBL4091793 0.79 ALDH1A1 (0.47) MEN1KMT2ALMNABLMTDP1
SCHEMBL29082974 0.77 MEN1 (0.39) MEN1KMT2ALMNABLMTDP1
SCHEMBL5859018 0.77 TSHR (0.58) KMT2ALMNATDP1ALDH1A3ALDH1A1
SCHEMBL1169909 0.76 TDP1 (0.41) MEN1KMT2ALMNABLMTDP1
SCHEMBL3043759 0.75 SRC (0.38) MEN1KMT2ALMNABLMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5773592-A COMPRISES A CHEMILUMINESCENT MOIETY, A PHOTOCHROMIC MOIETY AND A BIOLOGICALLY ACTIVE AGENT CAPABLE OF BEING RELEASED MILLS RANDELL LEE (US) 1998-06-30 US disclosed