Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7871606 | 0.78 | GPR119 (0.45) | GPR119KDM4EPKMTGFBR1FAAH | |
| SCHEMBL8712463 | 0.77 | GPR119 (0.43) | GPR119KDM4EPKMFAAHTHRB | |
| SCHEMBL7868708 | 0.77 | GPR119 (0.43) | GPR119KDM4EPKMTGFBR1THRB | |
| SCHEMBL8444736 | 0.74 | KDM4E (0.59) | GPR119KDM4EPKMTGFBR1THRB | |
| SCHEMBL7875427 | 0.74 | GPR119 (0.46) | GPR119KDM4EGRM5THRBMAPT | |
| SCHEMBL3138251 | 0.73 | IDH1 (0.49) | GPR119KDM4EPKMTGFBR1FAAH | |
| SCHEMBL6011556 | 0.71 | GPR119 (0.62) | GPR119KDM4EPKMFAAHTHRB | |
| SCHEMBL31192689 | 0.71 | KDM4E (0.52) | GPR119KDM4EPKMTGFBR1FAAH | |
| SCHEMBL1532924 | 0.71 | GPR119 (0.57) | GPR119KDM4EPKMGRM5 | |
| SCHEMBL5763005 | 0.71 | GPR119 (0.51) | GPR119KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826686-A2 | Tricyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |