Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7871606 | 0.95 | GPR119 (0.45) | GPR119FAAHKDM4EPKMMAPT | |
| SCHEMBL7868708 | 0.91 | GPR119 (0.43) | GPR119KDM4EPKMMAPTTHRB | |
| SCHEMBL8713586 | 0.86 | KDM1A (0.35) | — | |
| SCHEMBL8713342 | 0.84 | DRD2 (0.34) | KDM4E | |
| SCHEMBL7863517 | 0.83 | GPR119 (0.46) | GPR119FAAHKDM4EPKM | |
| SCHEMBL7875427 | 0.82 | GPR119 (0.46) | GPR119KDM4EMAPTTHRB | |
| SCHEMBL8717917 | 0.81 | KDM1A (0.34) | KDM4E | |
| SCHEMBL7871693 | 0.79 | GPR119 (0.43) | GPR119FAAHKDM4EPKM | |
| SCHEMBL8712812 | 0.77 | GPR119 (0.43) | GPR119FAAHKDM4EPKMMAPT | |
| Hydrochloric Acid SCHEMBL8712952 | 0.74 | STK4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10120568-A | — | — | None | — | — | JP | disclosed |
| JP-H10120568-A | PREVENTIVE AND THERAPEUTIC AGENT FOR GLOMERULAR NEPHRITIS | TAKEDA CHEM IND LTD | 1998-05-12 | — | — | JP | disclosed |
| EP-0826686-A2 | Tricyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |