Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 5/20 | 0.58 |
| ▸ | ERAP2 | Q6P179 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716030 | 0.82 | ANPEP (0.40) | ANPEPERAP2KDM4ESMN1; SMN2LMNA | |
| SCHEMBL9564518 | 0.77 | ANPEP (0.68) | ANPEPERAP2KDM4EHTTSMN1; SMN2 | |
| SCHEMBL9316055 | 0.77 | ANPEP (0.68) | ANPEPERAP2KDM4EHTTSMN1; SMN2 | |
| SCHEMBL9315989 | 0.77 | ANPEP (0.68) | ANPEPERAP2KDM4EHTTSMN1; SMN2 | |
| SCHEMBL18569456 | 0.75 | KDM4E (0.59) | ANPEPERAP2KDM4EHTTSMN1; SMN2 | |
| SCHEMBL14634284 | 0.74 | KDM4E (0.52) | ANPEPERAP2KDM4EHTTSMN1; SMN2 | |
| SCHEMBL9746636 | 0.72 | ANPEP (0.60) | ANPEPERAP2KDM4ESMN1; SMN2MMP2 | |
| SCHEMBL16111997 | 0.72 | ANPEP (0.60) | ANPEPERAP2KDM4ESMN1; SMN2MMP2 | |
| SCHEMBL11768023 | 0.71 | KDM4E (0.48) | ANPEPERAP2KDM4EHTTSMN1; SMN2 | |
| SCHEMBL7790207 | 0.70 | ANPEP (0.58) | ANPEPERAP2KDM4EHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0642518-B1 | PHOSPHONOSULFONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMA (US) | 1998-08-05 | — | — | EP | disclosed |
| US-5731299-A | OSTEOPOROSIS; RHEUMATOID ARTHRITIS | THE PROCTER & GAMBLE COMPANY (US) | 1998-03-24 | — | — | US | disclosed |
| CN-1087640-A | Novel phosphonosulfonate compounds, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism | PROCTER & GAMBLE PHARMA (US) | 1994-06-08 | — | — | CN | disclosed |