Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 5/20 | 0.68 |
| ▸ | ERAP2 | Q6P179 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9316055 | 1.00 | ANPEP (0.68) | ANPEPERAP2KDM4EHTTSMN1; SMN2 | |
| SCHEMBL9315989 | 1.00 | ANPEP (0.68) | ANPEPERAP2KDM4EHTTSMN1; SMN2 | |
| SCHEMBL7838696 | 0.82 | ANPEP (0.47) | ANPEPERAP2KDM4EMMP2MMP8 | |
| SCHEMBL16111997 | 0.79 | ANPEP (0.60) | ANPEPERAP2KDM4ESMN1; SMN2MMP2 | |
| SCHEMBL9746636 | 0.79 | ANPEP (0.60) | ANPEPERAP2KDM4ESMN1; SMN2MMP2 | |
| SCHEMBL8713138 | 0.77 | ANPEP (0.58) | ANPEPERAP2KDM4EHTTSMN1; SMN2 | |
| SCHEMBL7790207 | 0.77 | ANPEP (0.58) | ANPEPERAP2KDM4EHTTSMN1; SMN2 | |
| SCHEMBL9315972 | 0.73 | ANPEP (0.46) | ANPEPERAP2KDM4EHTTSMN1; SMN2 | |
| SCHEMBL9311100 | 0.73 | ANPEP (0.46) | ANPEPERAP2KDM4EHTTSMN1; SMN2 | |
| SCHEMBL9316059 | 0.73 | ANPEP (0.46) | ANPEPERAP2KDM4EHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522576-A2 | Aminoethane-1,1-bisphosphonic acids and aminoethane-1,1-alkylphospinic/phosphonic acids, process of their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-01-13 | — | — | EP | disclosed |