Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.60 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.60 |
| ▸ | MMP2 | P08253 | 7/20 | 0.48 |
| ▸ | CA12 | O43570 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | MMP1 | P03956 | 4/20 | 0.48 |
| ▸ | MMP8 | P22894 | 3/20 | 0.48 |
| ▸ | MMP3 | P08254 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746636 | 1.00 | ANPEP (0.60) | ANPEPERAP2MMP2CA12CA1 | |
| SCHEMBL9315989 | 0.79 | ANPEP (0.68) | ANPEPERAP2MMP2CA12CA1 | |
| SCHEMBL9564518 | 0.79 | ANPEP (0.68) | ANPEPERAP2MMP2CA12CA1 | |
| SCHEMBL9316055 | 0.79 | ANPEP (0.68) | ANPEPERAP2MMP2CA12CA1 | |
| SCHEMBL9747664 | 0.77 | MMP2 (0.53) | ANPEPERAP2MMP2CA12CA1 | |
| SCHEMBL7079587 | 0.75 | MMP2 (0.52) | ANPEPERAP2MMP2CA12CA1 | |
| SCHEMBL9747663 | 0.74 | ANPEP (0.41) | ANPEPERAP2MMP2CA12CA1 | |
| SCHEMBL11692884 | 0.73 | LMNA (0.57) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL10417529 | 0.73 | ANPEP (0.40) | ANPEPERAP2MMP2CA12CA1 | |
| Phosphoric Acid SCHEMBL9860603 | 0.72 | ALDH1A1 (0.67) | ANPEPERAP2MMP2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014160729-A1 | COMPOSITION AND METHOD FOR TREATING CANCER | CELLWORKS RESEARCH INDIA PVT. LTD (IN) | 2014-10-02 | — | — | WO | disclosed |