Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 5/20 | 1.00 |
| ▸ | CHRNA4 | P43681 | 3/20 | 1.00 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713172 | 1.00 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| Oxalic Acid SCHEMBL8715713 | 0.95 | CHRNB2 (0.90) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| Oxalic Acid SCHEMBL8715717 | 0.95 | CHRNB2 (0.90) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| Oxalic Acid SCHEMBL8716091 | 0.95 | CHRNB2 (0.90) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| SCHEMBL8713197 | 0.89 | CHRNB2 (0.80) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| SCHEMBL8713200 | 0.89 | CHRNB2 (0.80) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| Oxalic Acid SCHEMBL8712991 | 0.84 | CHRNB2 (0.73) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| Oxalic Acid SCHEMBL8712993 | 0.84 | CHRNB2 (0.73) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| SCHEMBL9217892 | 0.82 | CHRNB2 (0.70) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| SCHEMBL9217890 | 0.82 | CHRNB2 (0.70) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871627-A1 | NOVEL SUBSTITUTED AZACYCLIC OR AZABICYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-10-21 | — | — | EP | claimed |
| WO-1997011073-A1 | NOVEL SUBSTITUTED AZACYCLIC OR AZABICYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1997-03-27 | — | — | WO | claimed |
| EP-0871627-A1 | NOVEL SUBSTITUTED AZACYCLIC OR AZABICYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997011073-A1 | NOVEL SUBSTITUTED AZACYCLIC OR AZABICYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1997-03-27 | — | — | WO | disclosed |