⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713203 | 1.00 | — | — | |
| SCHEMBL8712472 | 0.81 | — | — | |
| SCHEMBL9081580 | 0.80 | FDPS (0.39) | — | |
| SCHEMBL9218779 | 0.71 | FKBP5 (0.31) | — | |
| SCHEMBL9083443 | 0.68 | FKBP5 (0.34) | — | |
| SCHEMBL2945310 | 0.63 | — | — | |
| SCHEMBL2945313 | 0.63 | — | — | |
| SCHEMBL8713222 | 0.63 | FDPS (0.64) | — | |
| Hydrochloric Acid SCHEMBL8475913 | 0.62 | FKBP5 (0.34) | — | |
| SCHEMBL7852982 | 0.61 | FDPS (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0642518-B1 | PHOSPHONOSULFONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMA (US) | 1998-08-05 | — | — | EP | disclosed |
| US-5731299-A | OSTEOPOROSIS; RHEUMATOID ARTHRITIS | THE PROCTER & GAMBLE COMPANY (US) | 1998-03-24 | — | — | US | disclosed |
| EP-0642518-A1 | PHOSPHONOSULFONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMACEUTICALS (US) | 1995-03-15 | — | — | EP | disclosed |
| CN-1087640-A | Novel phosphonosulfonate compounds, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism | PROCTER & GAMBLE PHARMA (US) | 1994-06-08 | — | — | CN | disclosed |
| WO-1993024495-A1 | PHOSPHONOSULFONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1993-12-09 | — | — | WO | disclosed |