Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3895308 | 0.80 | DGAT1 (0.50) | DGAT1MAPTALDH1A1USP2SMN1; SMN2 | |
| SCHEMBL1456408 | 0.80 | DGAT1 (0.50) | DGAT1MAPTALDH1A1TSHRUSP2 | |
| SCHEMBL8207418 | 0.77 | DGAT1 (0.52) | DGAT1ALDH1A1TSHRUSP2SMN1; SMN2 | |
| SCHEMBL20565054 | 0.77 | DGAT1 (0.52) | DGAT1ALDH1A1TSHRUSP2SMN1; SMN2 | |
| SCHEMBL362903 | 0.77 | DGAT1 (0.52) | DGAT1ALDH1A1TSHRUSP2SMN1; SMN2 | |
| SCHEMBL2308323 | 0.76 | DGAT1 (0.46) | DGAT1MAPT | |
| SCHEMBL5249575 | 0.74 | DGAT1 (0.44) | DGAT1MAPT | |
| SCHEMBL3141601 | 0.73 | DGAT1 (0.79) | DGAT1ALDH1A1TSHRUSP2SMN1; SMN2 | |
| SCHEMBL307610 | 0.73 | DGAT1 (0.55) | DGAT1ALDH1A1USP2SMN1; SMN2 | |
| SCHEMBL10892362 | 0.72 | DGAT1 (0.48) | DGAT1ALDH1A1TSHRUSP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821222-A | NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-10-13 | — | — | US | disclosed |
| US-5624897-A | PARASITICIDES, NEMATOSIDES OF CYCLIC PEPTIDE LACTONES FOR VETERINARY MEDICINE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-29 | — | — | US | disclosed |