Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4246491 | 0.90 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL3895308 | 0.78 | DGAT1 (0.50) | DGAT1MAPT | |
| SCHEMBL1456408 | 0.78 | DGAT1 (0.50) | DGAT1MAPT | |
| SCHEMBL14213166 | 0.78 | DGAT1 (0.50) | DGAT1CA14 | |
| SCHEMBL1714208 | 0.78 | DGAT1 (0.50) | DGAT1CA14 | |
| SCHEMBL22296098 | 0.78 | DGAT1 (0.50) | DGAT1CA14 | |
| SCHEMBL1405453 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL28000852 | 0.76 | DGAT1 (0.48) | DGAT1CA14 | |
| SCHEMBL8713356 | 0.76 | DGAT1 (0.48) | DGAT1MAPT | |
| SCHEMBL15147713 | 0.74 | DGAT1 (0.46) | DGAT1CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110536885-B | Process for producing difluoromethylene compound | 佐藤制药株式会社 | 2024-03-08 | — | — | CN | disclosed |
| US-11084792-B2 | Method for producing difluoromethylene compound | SATO PHARMACEUTICAL CO., LTD. (JP) | 2021-08-10 | — | — | US | disclosed |
| US-20200190038-A1 | METHOD FOR PRODUCING DIFLUOROMETHYLENE COMPOUND | SATO PHARMACEUTICAL CO., LTD. (JP) | 2020-06-18 | — | — | US | disclosed |
| EP-3617197-A1 | METHOD FOR PRODUCING DIFLUOROMETHYLENE COMPOUND | Sato Pharmaceutical Co., Ltd. (JP) | 2020-03-04 | — | — | EP | disclosed |
| US-8304443-B2 | Indazole derivatives | ASAHI KASEI PHARMA CORPORATION (JP) | 2012-11-06 | — | — | US | disclosed |
| US-20120225909-A1 | INDAZOLE ANALOG | ASAHI KASEI PHARMA CORPORATION (JP) | 2012-09-06 | — | — | US | disclosed |
| EP-2484668-A1 | INDAZOLE ANALOGUE | Asahi Kasei Pharma Corporation (JP) | 2012-08-08 | — | — | EP | disclosed |
| EP-2351742-A1 | INDAZOLE DERIVATIVE | Asahi Kasei Pharma Corporation (JP) | 2011-08-03 | — | — | EP | disclosed |
| US-20100152265-A1 | INDAZOLE DERIVATIVES | ASAHI KASEI PHARMA CORPORATION (JP) | 2010-06-17 | — | — | US | disclosed |
| US-20060293343-A1 | Pyrimidine derivatives | ASAHI KASEI PHARMA CORPORATION (JP) | 2006-12-28 | — | — | US | disclosed |
| US-5827634-A | FOR DEEP ULTRAVIOLET EXPOSURE; RESOLUTION | SHIPLEY COMPANY, L.L.C. (US) | 1998-10-27 | — | — | US | disclosed |
| US-5763536-A | PHOTORESIST BINDER CONSISTING OF NOVOLAK RESIN OR POLYVINYLPHENOL RESIN | SHIPLEY COMPANY, L.L.C. (US) | 1998-06-09 | — | — | US | disclosed |
| US-5731386-A | Polymer for positive acid catalyzed resists | SHIPLEY COMPANY, L.L.C. (US) | 1998-03-24 | — | — | US | disclosed |
| US-5700624-A | Positive acid catalyzed resists having an alkali soluble resin with acid labile groups and inert blocking groups | SHIPLEY COMPANY, L.L.C. (US) | 1997-12-23 | — | — | US | disclosed |
| US-5618951-A | REACTING A CHLORODIFLUOROACETATE WITH A HALOSILANE USING AN UREA SILVENT AND A REDUCING AGENT | ELI LILLY AND COMPANY (US) | 1997-04-08 | — | — | US | disclosed |
| EP-0742490-A1 | Positive acid catalized resists | Shipley Company LLC (US) | 1996-11-13 | — | — | EP | disclosed |
| EP-0655454-A1 | Process for preparing 2,2-difluoroketene silyl acetals and a,a-difluoro-b-silyloxy-1,3-dioxolane-4-propanoic acid esters | ELI LILLY AND COMPANY (US) | 1995-05-31 | — | — | EP | disclosed |
| US-5384229-A | Resin with acid labile groups, photoacid generator, photoresists, printed circuits | SHIPLEY COMPANY INC. (US) | 1995-01-24 | — | — | US | disclosed |
| US-5362600-A | Radiation sensitive compositions comprising polymer having acid labile groups | SHIPLEY COMPANY INC. (US) | 1994-11-08 | — | — | US | disclosed |
| US-5258257-A | Radiation sensitive compositions comprising polymer having acid labile groups | SHIPLEY COMPANY INC. (US) | 1993-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120225909-A1 | INDAZOLE ANALOG | ADRB3, ADRB1, ADRB2 | DGAT1 1778/4885MAPT 1048/4885CA14 4260/4885 |
| US-20060293343-A1 | Pyrimidine derivatives | PDE4A, PDE4B, PDE5A | DGAT1 2182/4885MAPT 3800/4885CA14 2302/4885 |
| US-20200190038-A1 | METHOD FOR PRODUCING DIFLUOROMETHYLENE COMPOUND | HACL2, MGLL, ABL1 | DGAT1 597/4885MAPT 4687/4885CA14 3464/4885 |
| US-20100152265-A1 | INDAZOLE DERIVATIVES | ADRB3, INSR, ADRB1 | DGAT1 1010/4885MAPT 748/4885CA14 3770/4885 |
| US-11084792-B2 | Method for producing difluoromethylene compound | HACL2, MGLL, ABL1 | DGAT1 597/4885MAPT 4687/4885CA14 3464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.