Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 9/20 | 0.67 |
| ▸ | HTR3A | P46098 | 8/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713385 | 1.00 | HTR4 (0.67) | HTR4HTR3ACYP3A4ALDH1A1TSHR | |
| SCHEMBL8714407 | 1.00 | HTR4 (0.67) | HTR4HTR3ACYP3A4ALDH1A1TSHR | |
| SCHEMBL8714409 | 1.00 | HTR4 (0.67) | HTR4HTR3ACYP3A4ALDH1A1TSHR | |
| SCHEMBL8714841 | 0.90 | HTR4 (0.82) | HTR4HTR3ACYP3A4 | |
| SCHEMBL8714839 | 0.90 | HTR4 (0.82) | HTR4HTR3ACYP3A4 | |
| SCHEMBL8719023 | 0.88 | HTR3A (0.54) | HTR4HTR3A | |
| SCHEMBL8717114 | 0.88 | HTR3A (0.54) | HTR4HTR3A | |
| SCHEMBL8717118 | 0.88 | HTR3A (0.54) | HTR4HTR3A | |
| SCHEMBL8719019 | 0.88 | HTR3A (0.54) | HTR4HTR3A | |
| SCHEMBL8714353 | 0.88 | HTR4 (0.52) | HTR4HTR3ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708105-B1 | 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO (JP) | 1998-12-23 | — | — | EP | disclosed |
| EP-0708105-A1 | 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |