Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 4/20 | 0.41 |
| ▸ | LAP3 | P28838 | 3/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 2/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713410 | 1.00 | ANPEP (0.41) | ANPEPLAP3ERAP1FDPSALDH1A1 | |
| SCHEMBL28342575 | 0.78 | FDPS (0.34) | ANPEPLAP3ERAP1FDPSALDH1A1 | |
| SCHEMBL26310696 | 0.76 | ANPEP (0.42) | ANPEPLAP3ERAP1FDPSALDH1A1 | |
| SCHEMBL8933408 | 0.76 | — | — | |
| SCHEMBL4536812 | 0.76 | — | — | |
| SCHEMBL5745180 | 0.76 | LAP3 (0.54) | ANPEPLAP3ERAP1FDPSALDH1A1 | |
| SCHEMBL5745177 | 0.76 | LAP3 (0.54) | ANPEPLAP3ERAP1FDPSALDH1A1 | |
| SCHEMBL12570893 | 0.76 | FDPS (0.59) | ANPEPLAP3ERAP1FDPSALDH1A1 | |
| SCHEMBL701768 | 0.72 | — | — | |
| SCHEMBL601976 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871454-A4 | — | — | 1998-11-25 | — | — | EP | disclosed |
| EP-0871454-A1 | PHOSPHOROUS-CONTAINING CYSTEINE AND SERINE PROTEASE INHIBITORS | CEPHALON, INC. (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997003679-A1 | PHOSPHOROUS-CONTAINING CYSTEINE AND SERINE PROTEASE INHIBITORS | CEPHALON, INC. (US) | 1997-02-06 | — | — | WO | disclosed |