Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043090 | 0.87 | MAPT (0.35) | ALDH1A1MAPTTP53MAPK1LMNA | |
| SCHEMBL8032375 | 0.85 | ALDH1A1 (0.33) | ALDH1A1MAPTTP53MAPK1LMNA | |
| SCHEMBL8042297 | 0.83 | ALDH1A1 (0.40) | ALDH1A1MAPTTP53MAPK1LMNA | |
| SCHEMBL8034587 | 0.82 | RECQL (0.37) | ALDH1A1MAPTMAPK1LMNAHTT | |
| SCHEMBL8033650 | 0.81 | ALDH1A1 (0.34) | ALDH1A1MAPTTP53MAPK1LMNA | |
| SCHEMBL8043982 | 0.81 | ALDH1A1 (0.47) | ALDH1A1MAPTTP53MAPK1LMNA | |
| SCHEMBL8032724 | 0.80 | MAPT (0.33) | ALDH1A1MAPTTP53MAPK1LMNA | |
| SCHEMBL8033964 | 0.79 | SMN1; SMN2 (0.39) | ALDH1A1MAPTTP53LMNAHTT | |
| SCHEMBL8049019 | 0.79 | RECQL (0.47) | ALDH1A1MAPTTP53MAPK1LMNA | |
| SCHEMBL8046748 | 0.78 | RECQL (0.39) | ALDH1A1MAPTTP53MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998027092-A1 | THIAZOLE COMPOUNDS AND METHODS OF MODULATING SIGNAL TRANSDUCTION | SUGEN, INC. (US) | 1998-06-25 | — | — | WO | disclosed |