Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033927 | 0.91 | NPSR1 (0.40) | ALDH1A1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL8043580 | 0.89 | HTT (0.43) | ALDH1A1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL8033786 | 0.88 | MAPT (0.39) | ALDH1A1KMT2ANPSR1LMNANPC1 | |
| SCHEMBL8051249 | 0.85 | RAB9A (0.35) | SMN1; SMN2ALDH1A1LMNAPOLBGAA | |
| SCHEMBL8043236 | 0.84 | UBE2M (0.35) | ALDH1A1HTTTP53 | |
| SCHEMBL8043035 | 0.83 | MAPT (0.33) | ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL8042593 | 0.83 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL8037035 | 0.82 | CYP1A2 (0.34) | SMN1; SMN2ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL8042294 | 0.82 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8034114 | 0.81 | HTT (0.31) | ALDH1A1CYP2C19HTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |