Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 6/20 | 0.82 |
| ▸ | NOS3 | P29474 | 4/20 | 0.69 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.47 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21806238 | 0.93 | NOS2 (0.77) | NOS2NOS3TLR8NOS1TLR7 | |
| SCHEMBL21543718 | 0.90 | NOS2 (1.00) | NOS2NOS3TLR8NOS1 | |
| SCHEMBL30154750 | 0.90 | NOS2 (1.00) | NOS2NOS3TLR8NOS1 | |
| Hydrochloric Acid SCHEMBL7049624 | 0.89 | NOS2 (0.96) | NOS2NOS3TLR8NOS1 | |
| SCHEMBL30664052 | 0.82 | NOS2 (1.00) | NOS2NOS3TLR8NOS1 | |
| SCHEMBL11743612 | 0.82 | NOS2 (1.00) | NOS2NOS3TLR8NOS1 | |
| Hydrochloric Acid SCHEMBL7048556 | 0.80 | NOS2 (0.96) | NOS2NOS3TLR8NOS1 | |
| SCHEMBL9488515 | 0.79 | NOS2 (0.58) | NOS2NOS3TLR8SKP2TLR7 | |
| SCHEMBL7008513 | 0.78 | NOS2 (0.52) | NOS2NOS3TLR8SKP2 | |
| SCHEMBL28814991 | 0.78 | NOS2 (0.51) | NOS2NOS3TLR8SKP2TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846720-A | Methods of determining chemicals that modulate expression of genes associated with cardiovascular disease | ONCOGENE SCIENCE, INC. (US) | 1998-12-08 | — | — | US | disclosed |