Maleic Anhydride

Maleic Anhydride

SCHEMBL8713700

N#CC=CC=Cc1ccccc1.O=C1C=CC(=O)N1c1ccccc1.O=C1C=CC(=O)O1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 7/20 0.46
FAAH O00519 4/20 0.39
ALDH1A1 P00352 7/20 0.38
KMT2A Q03164 5/20 0.38
MAPT P10636 5/20 0.38
MAPK1 P28482 4/20 0.38
LMNA P02545 3/20 0.38
PKM P14618 2/20 0.38
MEN1 O00255 2/20 0.38
POLB P06746 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
KDM4E B2RXH2 1/20 0.38
NTSR1 P30989 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
HTT P42858 3/20 0.36
HSP90AA1 P07900 2/20 0.36
ATM Q13315 1/20 0.36
MAOB P27338 1/20 0.36
CMA1 P23946 1/20 0.34
MCL1 Q07820 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1448766 0.92 MGLL (0.55) MGLLFAAHALDH1A1KMT2AMAPT
Maleic Anhydride SCHEMBL148559 0.89 MAOB (0.45) ALDH1A1KMT2AMAPTMAPK1LMNA
Maleic Anhydride SCHEMBL28856601 0.84 MAOB (0.40) ALDH1A1KMT2AMAPTMAPK1LMNA
Cyclopentene SCHEMBL27975958 0.84 MGLL (0.45) MGLLFAAHALDH1A1KMT2AMAPT
Maleic Anhydride SCHEMBL9076211 0.79 MGLL (0.56) MGLLFAAHALDH1A1MAPK1PKM
Maleic Anhydride SCHEMBL17534910 0.78 MGLL (0.75) MGLLFAAHALDH1A1MAPK1PKM
Maleic Anhydride SCHEMBL10691759 0.77 MAOB (0.61) ALDH1A1KMT2AMAPTMAPK1LMNA
Styrene SCHEMBL27996115 0.76 MGLL (0.56) MGLLFAAHALDH1A1MAPK1PKM
Styrene SCHEMBL150226 0.76 MGLL (0.56) MGLLFAAHALDH1A1MAPK1PKM
SCHEMBL17741 0.75 MAOB (0.64) ALDH1A1KMT2AMAPTMAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115516029-A Thermoplastic resin composition and molded article using the same 乐天化学株式会社 2022-12-23 CN disclosed
EP-0629498-B1 Multi layered product comprising an ABS layer with a low rubber content and an ABS layer with a high rubber content GEN ELECTRIC (US) 1998-10-07 EP disclosed
US-5492966-A BI-LOBED: ONE RIGID, ONE RUBBERY; RUBBER LOBES EXHIBIT AFFINITY FOR EACH OTHER AND TEND TO AGGLOMERATE DURING COMPOUNDING TO GIVE LARGE RUBBER PARTICLE SIZES WITH REDUCED GLOSS GENERAL ELECTRIC COMPANY (US) 1996-02-20 US disclosed
US-5486407-A High rubber backing multi-layer ABS system which exhibits improved chemical resistance to HCFC blowing agents GENERAL ELECTRIC CO. (US) 1996-01-23 US disclosed
EP-0629498-A1 Multi layered product comprising an ABS layer with a low rubber content and an ABS layer with a high rubber content GENERAL ELECTRIC COMPANY (US) 1994-12-21 EP disclosed
EP-0564240-A1 Impact modified resin compositions GENERAL ELECTRIC COMPANY (US) 1993-10-06 EP disclosed
US-5047470-A Thermoplastic Blends GENERAL ELECTRIC COMPANY (US) 1991-09-10 US disclosed
EP-0363814-A2 Low-temperature impact blends of polycarbonate, graft copolymer and rigid copolymer GENERAL ELECTRIC COMPANY (US) 1990-04-18 EP disclosed