Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 6/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8710110 | 0.82 | ADORA2B (0.61) | ADORA2BADORA3TSHRHSD17B10ADORA2A | |
| SCHEMBL1946830 | 0.82 | ADORA2B (0.62) | ADORA2BADORA3ADORA2AADORA1MAPT | |
| SCHEMBL3226126 | 0.77 | ADORA1 (0.60) | ADORA2BADORA3ADORA2AADORA1 | |
| SCHEMBL1061950 | 0.76 | ADORA2A (0.53) | ADORA2BADORA3ADORA2AADORA1 | |
| SCHEMBL1945104 | 0.76 | ADORA2B (0.52) | ADORA2BADORA3ADORA2AADORA1 | |
| SCHEMBL12245132 | 0.72 | ADORA2A (0.55) | ADORA2BADORA3ADORA2AADORA1MAPT | |
| SCHEMBL1065789 | 0.72 | ADORA2B (0.73) | ADORA2BADORA3HSD17B10ADORA2AMEN1 | |
| SCHEMBL1947373 | 0.72 | ADORA2B (0.52) | ADORA2BADORA3ADORA2AADORA1 | |
| SCHEMBL8578138 | 0.72 | ADORA3 (0.56) | ADORA2BADORA3ADORA2AKMT2AADORA1 | |
| SCHEMBL9708336 | 0.71 | ADORA3 (0.46) | ADORA2BADORA3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840729-A | ATTENUATING COGNITIVE DEFICIT | MERRELL PHARMACEUTICALS INC. (US) | 1998-11-24 | — | — | US | disclosed |