Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | SMO | Q99835 | 1/20 | 0.45 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.44 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.44 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713805 | 0.90 | AVPR2 (0.55) | AVPR1AAVPR2AVPR1B | |
| SCHEMBL8713384 | 0.90 | HSD11B1 (0.48) | HSD11B1SMOAVPR1AAVPR2AVPR1B | |
| SCHEMBL8713499 | 0.87 | AVPR2 (0.43) | AVPR1AAVPR2AVPR1B | |
| SCHEMBL8717630 | 0.86 | AVPR1A (0.57) | HSD11B1SMOAVPR1AAVPR2AVPR1B | |
| Hydrochloric Acid SCHEMBL8719775 | 0.85 | HSD11B1 (0.46) | HSD11B1SMOAVPR1AAVPR2AVPR1B | |
| SCHEMBL7346236 | 0.83 | AVPR1A (0.63) | HSD11B1AVPR1AAVPR2AVPR1B | |
| SCHEMBL8716136 | 0.83 | AVPR1A (0.47) | HSD11B1AVPR1AAVPR2AVPR1B | |
| SCHEMBL8713623 | 0.81 | AVPR2 (0.54) | AVPR1AAVPR2AVPR1B | |
| SCHEMBL8713038 | 0.81 | HSD11B1 (0.49) | HSD11B1AVPR1AAVPR2 | |
| SCHEMBL8713915 | 0.80 | AVPR2 (0.54) | AVPR1AAVPR2AVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753677-A | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |