Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 6/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 7/20 | 0.45 |
| ▸ | PPARA | Q07869 | 7/20 | 0.45 |
| ▸ | PPARD | Q03181 | 6/20 | 0.45 |
| ▸ | PDE4A | P27815 | 3/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7692652 | 0.93 | NR1H3 (0.60) | NR1H3NR1H2PPARGPPARAPPARD | |
| SCHEMBL8711862 | 0.88 | NR1H2 (0.41) | NR1H3NR1H2PPARGPPARAPPARD | |
| SCHEMBL7699505 | 0.83 | NR1H3 (0.49) | NR1H3NR1H2PPARGPPARAPPARD | |
| SCHEMBL8708638 | 0.81 | NR1H3 (0.59) | NR1H3NR1H2MCHR1 | |
| SCHEMBL7701165 | 0.80 | HTR2C (0.56) | NR1H3NR1H2PDE4APDE4BPDE4C | |
| SCHEMBL8708142 | 0.79 | RAB9A (0.51) | NR1H3NR1H2PPARGPPARAPPARD | |
| SCHEMBL7692903 | 0.78 | NR1H3 (0.45) | NR1H3NR1H2PPARGPPARAPPARD | |
| SCHEMBL8708036 | 0.77 | QPCT (0.48) | NR1H3NR1H2PDE4APDE4BPDE4C | |
| SCHEMBL8707465 | 0.77 | PDE4A (0.44) | NR1H3NR1H2PPARGPPARAPPARD | |
| SCHEMBL8712042 | 0.75 | NR1H3 (0.42) | NR1H3NR1H2PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042666-A1 | NOVEL 3,4-DIALKOXYPHENYL DERIVATIVES AND THE USE THEREOF | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 1998-10-01 | — | — | WO | disclosed |